Master theses

Temperature-driven software for controlling laser therapies in biological tissue


Supervisor: Prof. Paola Saccomandi (paola.saccomandi@polimi.it)


Development of a software-based system with temperature feedback for controlling laser therapies in biological tissue

 

The increase of tissue temperature induced by laser is used to destroy tumors. This thesis focuses on the design of software aimed at using the temperature measured by sensors as feedback to control in real-time the laser operation. Skills and knowledge in fiber optic sensors, FEM simulations and LabVIEW will be acquired.

 

The thesis will be performed in the Department of Mechanical Engineering, in the Laboratory of Measurements for Biomedical Applications (B22).

Hyperspectral imaging for biomedical applications


Supervisor: Prof. Paola Saccomandi (paola.saccomandi@polimi.it)


Feature-extraction algorithms for hyperspectral imaging

This thesis focuses on the investigation and development of an image processing approach for extracting features from hyperspectral data of biological tissue. Skills and knowledge in hyperspectral camera systems, Matlab, and IR thermography will be acquired.

 

The thesis will be performed in the Department of Mechanical Engineering, in the Laboratory of Measurements for Biomedical Applications (B22).

Laser-nanoparticles interaction for photothermal therapy


Supervisor: Prof. Paola Saccomandi (paola.saccomandi@polimi.it)


This thesis focuses on the investigation and development of methods in the field of light-nanomaterials interaction, useful to improve photothermal therapies. Skills and knoweldge in nanotechnology, thermography and Monte Carlo simulations will be acquired.

 

The thesis will be performed in the Department of Mechanical Engineering, in the Laboratory of Measurements for Biomedical Applications (B22).

Laser-nanoparticles interaction for drug delivery and therapy


Supervisor: Prof. Paola Saccomandi (paola.saccomandi@polimi.it)


Laser-nanoparticles interaction for drug delivery and therapy
This thesis focuses on the investigation and development of methods in the field of light-nanomaterials interaction, useful to improve therapies and drug delivery. Skills and knowledge in nanotechnology, thermography, and chemistry will be acquired.

The thesis will be performed in the Department of Mechanical Engineering, in the Laboratory of Measurements for Biomedical Applications (B22), and with the ORT Braude Academic College of Engineering in Israel (Dr. Iris Weitz).

New fiber optic pressure sensors for the human body


Supervisor: Prof. Alfredo Cigada (alfredo.cigada@polimi.it), Prof. Paola Saccomandi

AIM: develop a new miniaturized pressure sensor to be used inside the human body

 

The need to measure pressure inside the human body requires miniaturized sensors: the project aims at developing a new device based on fiber optic sensors, which can eventually be inserted into a catheter. Skills and knoweldge in fiber optic sensors, data acquisition software, laboratory activity will be acquired.

 

The thesis will be performed in the Department of Mechanical Engineering, in the Laboratory of Measurements for Biomedical Applications (B22).

Device for thermal ablation


Supervisor: Prof. Paola Saccomandi (paola.saccomandi@polimi.it)


Optimization of a thermal ablation device
 The increase of tissue temperature induced by several devices (based on radiofrequency, microwave, laser, …) is used to treat tumors. This thesis focuses on the optimization of a device aimed at delivering real-time controlled energy in biological tissues. Skills and knowledge in fiber optic sensors, data processing, and s             pecific software will be acquired.      

The thesis will be performed in collaboration with the Departement of Mechanical Engineering, in the Laboratory of Measurements for Biomedical Applications (B22), and with the Nazarbayev University in Astana, Kazakhstan (prof. Daniele Tosi).